• Clostridium Botulinum Toxin Type A (100U)
  A purified neurotoxin protein that temporarily relaxes targeted muscles to smooth facial wrinkles and reduce muscle-related conditions.
• Human Serum Albumin (0.5 mg)
  A stabilizing protein that helps maintain the effectiveness and safety of the botulinum toxin during storage and after reconstitution.
• Sodium Chloride (0.9 mg)
  An isotonic agent that ensures the solution is safe and compatible with the body when injected.

When injected into targeted muscles, Wondertox prevents excessive muscle movement that causes dynamic wrinkles, such as frown lines between the eyebrows. By reducing these repetitive contractions, the skin above the muscle relaxes and smooths out, resulting in fewer visible wrinkles and a refreshed appearance. The effect is temporary, allowing natural facial expressions to gradually return as the nerve endings regenerate over time. This makes Wondertox suitable for those seeking a non-permanent solution for wrinkle reduction and facial rejuvenation. In addition to wrinkle improvement, this mechanism is also used in medical treatments such as relieving eyelid spasms (benign essential blepharospasm) and correcting muscle-related foot deformities.

Product preparation

Wondertox 100U comes as a powder in a sterile vial and must be prepared before use. Proper preparation ensures the product’s safety and effectiveness.

Materials Needed:

• Wondertox 100U vial
• 0.9% Sodium Chloride (non-preserved sterile saline)
• 30g 8mm 0.5cc Insulin Syringe
• Alcohol swabs
• Gloves

Preparation Steps:

1. Remove the vial from the refrigerator and allow it to reach room temperature.
2. Visually inspect the vial — it should be clear and contain a small amount of fine, white or light-yellow freeze-dried powder.
3. Gather all necessary materials, including sterile 0.9% saline, a syringe, alcohol swabs, and gloves.
4. Clean the rubber stopper of the vial with an alcohol swab before reconstitution.

How to dilute Wondertox 100U

Wondertox comes in a vial containing a fine powder containing 100 units of Botulinum toxin type A that needs to be diluted with 0.9% saline.

Note: The powder is very fine, so the vial may look empty. Rest assured that all units are present.

Step-by-Step Dilution Instructions:

1. Follow the following steps to dilute & reconstitute your toxin.
2. Take the vial out of the refrigerator and visually inspect: the vial should be colorless and transparent with a small quantity of white/light yellow powder.
3. Using the table below, draw Saline (0.9% Sodium Chloride) into a syringe and slowly add it to the Wondertox vial.
4. Gently and slowly swirl the vial to mix; do not shake excessively.
5. The reconstituted product should be kept in the refrigerator (2-8℃) and used within 24 hours

Note: Manufacturers recommend using the toxin within 24 hours of dilution, but research has shown that the reconstituted product remains stable for up to 5 weeks in the refrigerator (2-8℃).

Treatment areas

Wondertox 100U is primarily indicated for reducing wrinkles caused by muscle contractions. The most commonly treated facial area is the glabellar region (between the eyebrows). Depending on practitioner experience and assessment, it may also be used in other areas for cosmetic purposes.

• Glabellar region (frown lines between the eyebrows) 
• Forehead lines (off-label, practitioner dependent)
• Crow’s feet (lines around the outer eyes — subject to professional discretion)
• Periorbital area (for blepharospasm treatment)

Medical Treatment Areas

• Eyelids – Used for treating benign essential blepharospasm (involuntary eyelid muscle spasms).
• Lower limbs – For the treatment of equinus foot deformity caused by spasticity in children older than 2 years.

Notes: Wondertox is primarily designed and tested for glabellar lines and specific medical conditions. Use in other areas is determined by the treating professional based on their assessment, training, and regulatory guidelines.

Dosage and technique

Wondertox 100U should only be administered by licensed medical professionals with experience in botulinum toxin injections. The dosage and technique vary depending on the treatment purpose and area.

For glabellar lines (frown lines between the eyebrows):

• The typical treatment uses a total of 20 units, divided into 5 injection points with 0.1 mL (or 4 units per injection) per point.
• The injection is administered intramuscularly directly into the targeted muscles responsible for the wrinkles.

For benign essential blepharospasm, dosage and injection sites are determined individually based on patient characteristics, typically involving injections into the orbicularis oculi muscles to reduce spasms.

For equinus foot deformity due to spasticity in patients over 2 years old, the dosage and injection pattern depend on the severity, muscle mass, and specific needs, and must be administered by a trained medical professional experienced in pediatric botulinum toxin treatment.

Administration Technique:

• Use a fine needle (commonly included is a 30g 8mm 0.5cc insulin syringe) for precise intramuscular injections.
• The reconstituted solution should be injected slowly and evenly.
• Gently press the injection site after administration to minimize diffusion.
• Avoid excessive manipulation or massaging of the area after treatment.

Notes:

Wondertox should be used within 24 hours after reconstitution and kept refrigerated. Only trained professionals should determine the exact dosage and injection technique for each patient.

Post-treatment

After treatment, patients are advised to avoid rubbing or massaging the treated area, remain upright for several hours, and avoid strenuous activities for 24–48 hours to reduce the risk of unwanted side effects and ensure optimal results. Mild swelling or bruising may occur and usually resolves within a few days.